Top STEM GitHub Repositories & Tools (2026)

Free, open-source, offline-first Point of Sale for cafes, restaurants, and food businesses.

Interactive Tables and Data Grids for JavaScript

a fast systems programming language for high-performance software and gamedev: data-oriented, multi-paradigm, null-safe, safety checks, C-like syntax, C interop, native code/JIT via LLVM, C backend

The governed runtime for Python agents you can let act: policy on every action, durable runs, sandboxes, budgets, and the evidence of every run.

OpenELIS Global — open-source Laboratory Information System (LIS/LIMS) for clinical and public-health labs in 25+ countries. Java/Spring + React (Carbon), FHIR R4 native, Docker.

A SystemVerilog language server based on the Slang library.

Awesome Jev: source-backed open-source ecosystem radar, plain-language project discovery, and automatic GitHub sync

All in One PSA for MSPs, which Unifies client, contact, vendor, asset, license, domain, ssl certificate, password, documentation, file, network and location management with ticketing and billing capabilities, with a client portal on the side.

SystemVerilog compiler and language services

Neo.mjs is a self-evolving software organism: a professional end-to-end AI engineering team whose cross-model swarm inhabits live apps via Neural Link, Active Hybrid GraphRAG, DreamService, and self-healing loops.

Teams-first Multi-agent orchestration for Claude Code

SeaweedFS is a distributed storage system for object storage (S3), file systems, and Iceberg tables, designed to handle billions of files with O(1) disk access and effortless horizontal scaling.

Qdrant - High-performance, massive-scale Vector Database and Vector Search Engine for the next generation of AI. Also available in the cloud https://cloud.qdrant.io/

The Serenity Operating System 🐞

🐼 Universal, Type-Safe, CSS-in-JS Framework for Design Systems ⚡️

The Monorepo Platform that amplifies both developers and AI agents. Nx optimizes your builds, scales your CI, and fixes failed PRs automatically. Ship in half the time.

A free, powerful, multi-purpose tool that helps you monitor system resources, debug software and detect malware. Brought to you by Winsider Seminars & Solutions, Inc. @ https://windows-internals.com

Eigent: The Open Source Cowork Desktop - Local and Free Alternative to Claude Cowork and Codex

Apache ZooKeeper

Semantic tool routing and typed System One decisions for the Pi coding agent using TypeSafe Jev