Top PYPI GitHub Repositories & Tools (2026)

Open-source universal artifact registry. Drop-in Artifactory/Nexus alternative with 40+ package formats, security scanning, WASM plugins, and edge replication.

The Python Package Index

A library to train, evaluate, interpret, and productionize decision forest models such as Random Forest and Gradient Boosted Decision Trees.

Python's dir() for humans.

One config to rule all your AI agents: portable (every project, every session), effective (curated writing, routing, skills), and safer (destructive-command guard).

Aggregate results from bioinformatics analyses across many samples into a single report.