Top Python GitHub Repositories & Open Source Projects (2026)

Official repository for Spyder - The Scientific Python Development Environment

An Asynchronous Reinforcement Learning Engine for Omni-Modal Post-Training at Scale

[MIRROR] Package management system

high-performance linear attention kernel library built on TileLang

Astra plans and reviews; DeepSeek Flash builds. A native Codex workflow with phased tasks, verification, safe installation and reversible setup.

Tech internships & CS jobs tracker - 180 open software engineering internships from 4,300 employer job boards, auto-updated every 30 min with visa-sponsorship and H-1B sponsor data.

Your agent's favorite harness, built on Pydantic AI

Python bindings for access to the on-device model at the core of Apple Intelligence through the Foundation Models framework

The HIP Environment and ROCm Kit - A lightweight open source build system for HIP and ROCm

The largest collection of PyTorch image encoders / backbones. Including train, eval, inference, export scripts, and pretrained weights -- ResNet, ResNeXT, EfficientNet, NFNet, Vision Transformer (ViT), MobileNetV4, MobileNet-V3 & V2, RegNet, DPN, CSPNet, Swin Transformer, MaxViT, CoAtNet, ConvNeXt, and more

A library for generative social simulation

JEPA-Anything: Learning Predictive Models across Different Worlds

Declarative AI pipelines in one YAML file. Tokens, audio chunks, and video frames flow between isolated components. Compose 100+ components for models, agents, speech, vision, and live broadcast. Run local models, cloud APIs, or both. Inspired by docker-compose.

A pre-commit hook for Ruff.

TokenSpeed is a speed-of-light LLM inference engine.

Open-source AI Security Operations Center: alert fusion, LLM-agent triage, MITRE ATT&CK investigation, and a replayable decision ledger for every agent step. Self-hostable, runs with no API keys, MIT licensed. Ships an MCP server for Claude, Cursor and Continue.

AI conversations that actually remember. Never re-explain your project to your AI again. Join our Discord: https://discord.gg/tyvKNccgqN

MLX-VLM is a package for inference and fine-tuning of Vision Language Models (VLMs) on your Mac using MLX.

ZenML 🙏: One AI Platform from Pipelines to Agents. https://zenml.io.

ComfyUI node for MiniMax H3 that chains multiple video clips with motion context, disk caching, dynamic image references, audio reference support, and seamless final video/audio decoding.