Top SCIENTIFIC GitHub Repositories & Tools (2026)

ClearAI is a native DSH plugin that brings the Epistemic Loop to DeepSeek Harness.

The open-source AI research workbench for scientific research and agent workflows. Local-first, model-agnostic desktop app with extensible skills, MCP tools and connectors, Python/R execution and traceable artifacts for reproducible research on macOS, Windows and Linux.

The open-source AI workbench for scientific research

✨ The fundamental numerical library for JavaScript and TypeScript. ✨                   ⭐️ Star to support our work!

3D visualization and mesh analysis for science and engineering

Collect Lots of Shadowsocks, ShadowsocksR, Trojan, Vmess from Public Sources & Filter Best Nodes By Speed

Avogadro libraries provide 3D rendering, visualization, analysis and data processing useful in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas.

Open Data Cube analyses continental scale Earth Observation data through time

:gem: Feel++: Finite Element Embedded Language and Library in C++

Galactic Dynamics in python

Democratizing AI scientists with ToolUniverse

CasADi is a symbolic framework for numeric optimization implementing automatic differentiation in forward and reverse modes on sparse matrix-valued computational graphs. It supports self-contained C-code generation and interfaces state-of-the-art codes such as SUNDIALS, IPOPT etc. It can be used from C++, Python, Matlab/Octave, Julia or Javascript

Spack's community package recipes

The Go/XGo Interpreter

End to end human text analysis package, specifically suited for social media and social scientific applications. It is written in Python 3 and developed by the World Well-Being Project at the University of Pennsylvania and Stony Brook University.

ODE solver library in Rust

A Puppet Module to Manage Consul

a rust-native Modelica compiler for fast, composable, scientific computing

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

The Journal of Open Source Software