Top PYTHON GitHub Repositories & Tools (2026)

Awesome list of open-source startup alternatives to well-known SaaS products 🚀

Real-time intraday stock scanner for US equities with a browser dashboard you lay out yourself

If you live in the terminal, kitty is made for you! Cross-platform, fast, feature-rich, GPU based.

Your Friendly Open-Source Gen-AI Platform

Open source voice AI platform. Self-hosted alternative to Vapi and Retell. On Prem, BYOK across Speech to Speech or LLM/STT/TTS, with a visual workflow builder, MCP native and telephony support.

An orchestration platform for the development, production, and observation of data assets.

The ultimate RAG for your monorepo. Query, understand, and edit multi-language codebases with the power of AI and knowledge graphs

The #1 AI Harness for Building Resumes, PDFs, Cover Letters & more, locally with 100+ LLMs support.

Extremely fast Query Engine for DataFrames, written in Rust

Open-source inference server and production cluster for all the models your agent needs.

Flagsmith is an open-source feature flag platform with remote config, experimentation, and self-hosted or cloud deployment options.

A fast browser agent: Jev picks each action from what is on the page, an LLM reads and plans, and every claim in an answer cites a quote from the page.

The Database Toolkit for Python

🎬 Ultimate AI Auto-Clipper — Transform long-form videos & podcasts into viral shorts! Features smart face-tracking, kinetic karaoke subtitles, contextual B-roll, AI voice-overs, and auto-uploaders (YouTube/FB). Powered by Whisper, Gemini, MediaPipe, & Pyannote.

The only browser automation that bypasses anti-bot systems. AI writes network hooks, clones UIs pixel-perfect via simple chat.

PipesHub is an open-source platform for securely connecting enterprise knowledge to AI. Give AI agents trusted context and your team permission-aware search with verified citations across your business systems.

A fast type checker and language server for Python

Open Lakehouse Format for Multimodal AI. Convert from Parquet in 2 lines of code for 100x faster random access, vector index, and data versioning. Compatible with Pandas, DuckDB, Polars, Pyarrow, and PyTorch with more integrations coming..

Open Source HR and Payroll Software

Official repository for Spyder - The Scientific Python Development Environment