Top GLOBAL GitHub Repositories & Tools (2026)

Local-first AI coding agent desktop: Electron + Rust host core + pi Agent Harness + user-installable plugins

The most popular open source electronic health records and medical practice management solution.

Tsugi Admin, Developer, and Management Console (pls join the dev list)

OpenELIS Global — open-source Laboratory Information System (LIS/LIMS) for clinical and public-health labs in 25+ countries. Java/Spring + React (Carbon), FHIR R4 native, Docker.

macOS menu-bar app for fine-grained VPN routing: bypass the VPN for chosen domains/services, force others through it, or (Custom mode) route each domain/subnet out a specific egress — direct, a specific VPN, an HTTP/SOCKS5 proxy, or a Tailscale peer. Includes a vpnb CLI.

Bongo cat OBS overlay & bongo cat keyboard plugin: bongo cat steam alternative, bongo cat game, bongo cat gif, bongo cat download pc, bongo cat github, github bongo cat, bongo cat v2, bongo cat plugin, Streamlabs, gamepad, Twitch, Windows Mac, under 1% CPU. ▼

A high performance Vulkan/DX12 game engine in C++ & C#