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refresh-bio/agc

Assembled Genomes Compressor (AGC) squeezing 290 GB of Human Pangenome Project assemblies down to <1.5 GB (>190× ratio), with sample and contig extraction in seconds.

C++ ◇ compression MIT
★187STARS
⑂20FORKS
!12ISSUES
🏆#9,742GLOBAL RANK
🔥1DAYS TRENDING
🚀
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Momentum

+10

STARS · LAST 30 DAYS

1

PER DAY

#727

MOST-STARRED C++

Window7 days30 days90 days
Stars gained+7+10+90
Per day111
Forks gained+1+3+10

agc gained 10 stars in the last 30 days, about 1 a day, and now has 187. It is about 5 years old and has averaged roughly 37 stars a year. It ranks #727 among C++ repositories and #9,742 across all languages on GitHubRepo.

Trending Record

agc has maintained a continuous presence across global trending indexes, peaking at #9140. Below is the 30-day activity profile:

💡 Overview

agc is an open-source project written in C++: Assembled Genomes Compressor (AGC) squeezing 290 GB of Human Pangenome Project assemblies down to <1.5 GB (>190× ratio), with sample and contig extraction in seconds.

Engineered for speed, consistency, and developer ease, it solves common hurdles in compression, compression-algorithm, fasta. It provides clear interfaces, comprehensive configuration options, and seamless integration with existing tools across the modern development stack.

⚡ Key Features

1

Optimized execution pipeline written in C++ for predictable speed.

2

Zero-friction configuration with comprehensive sensible defaults out of the box.

3

Cross-platform runtime support across Linux, macOS, and Windows environments.

4

Strong typing and modular architecture designed for easy extension and maintainability.

5

Standardized CLI and API interfaces for smooth integration into CI/CD workflows.

6

Active community maintenance with regular dependency updates and security patches.

📥 Installation

terminal
$ git clone https://github.com/refresh-bio/agc.git
cd agc

⚙ System Requirements

Platforms

  • • macOS
  • • Linux
  • • Windows

Runtime & Dependencies

C++20 compliant compiler (GCC 11+, Clang 13+, MSVC)

Architecture

x86_64, ARM64 (Apple Silicon & Graviton)

🧠 How It Works

agc coordinates its core functionality through a modular C++ pipeline. It parses configuration parameters, validates inputs, and resolves dependencies asynchronously. By minimizing runtime overhead and keeping allocations localized, it delivers predictable performance in both local development environments and automated production workloads.

🎯 Production Use Cases

Production System Integration

Embed agc into C++ backend services to handle core application logic.

CI/CD Automated Pipelines

Run automated validation, builds, and integration suites during deployments.

Developer Tooling & Workflows

Accelerate developer onboarding with pre-configured project utilities.

Open Source Extension

Fork and customize internal modules under the repository's open MIT license.

🚀 Getting Started

1

Install agc using your package manager: `git clone https://github.com/refresh-bio/agc.git`

2

Initialize your project workspace or configuration file for agc.

3

Import agc into your codebase or invoke it directly from your terminal.

4

Execute your test suite or run `agc --help` to verify successful setup.

👍 Strengths

Active community backing with 187 GitHub stars and verified adoption.
Permissive open-source distribution under the MIT license.
Built in C++ for high execution speed and developer familiarity.
Cross-platform compatibility across modern Linux, macOS, and Windows environments.
Clean modular design allowing flexible configuration and pipeline integration.

⚠️ Considerations

Requires familiarity with C++ and modern CLI workflows.
Ecosystem extensions may require manual configuration depending on environment constraints.
Active development roadmap means breaking API changes may occur across major versions.

⇄ Alternatives & Direct Competitors

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👥 Who Should Use This

Developers and engineering teams building with C++, seeking reliable, tested, and actively maintained tooling for production workloads.

🏆 Nearby in the Rankings

refresh-bio/agc is currently ranked #9,742 by stars across every repository tracked on GitHubRepo. These are adjacent projects:

RankRepositoryLanguageStarsAction
#9,719 personalrobotics/ssik Python ★ 188 Compare ↗
#9,719 MorpheApp/morphe-patcher Kotlin ★ 188 Compare ↗
#9,719 mkrueger/icy_tools Rust ★ 188 Compare ↗
#9,719 MiniMax-AI/OpenAgentCore Go ★ 188 Compare ↗
#9,719 husseinhareb/hw-monitor TypeScript ★ 188 Compare ↗
#9,742 refresh-bio/agc This Project C++ ★ 187
#9,742 Xu123-Bob/Baize JavaScript ★ 187 Compare ↗
#9,742 dicom/ruby-dicom Ruby ★ 187 Compare ↗
#9,742 wardencommunity/sinatra_warden Ruby ★ 187 Compare ↗
#9,742 hebcal/hebcal Go ★ 187 Compare ↗
#9,742 EnviroDIY/Arduino-SDI-12 C++ ★ 187 Compare ↗

Frequently Asked Questions

What does agc do? +

Assembled Genomes Compressor (AGC) squeezing 290 GB of Human Pangenome Project assemblies down to <1.5 GB (>190× ratio), with sample and contig extraction in seconds.

What language is agc written in? +

The primary language is C++. Topics include: compression, compression-algorithm, fasta, genomes.

Is agc actively maintained? +

Yes, the last recorded push was on Oct 5, 2026 with 12 open issues being tracked.

How many stars does agc have? +

agc has 187 stars and 20 forks on GitHub.

How does agc rank among GitHub repositories? +

With 187 stars, refresh-bio/agc is ranked #9,742 globally across all repositories tracked on GitHubRepo and #727 among C++ projects.

What license is agc distributed under? +

The repository reports a MIT license. Always verify the repository LICENSE file for legal terms.

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