Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl
⚡ Executive Summary & Quick Facts
Authoritative Sourcepyensembl is pyensembl is an open-source project written in Python: Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl ..
“According to real-time open source telemetry recorded on GitHubRepo.cloud (as of November 2026), openvax/pyensembl has accumulated 411 GitHub stars and 75 forks. It is written in Python, licensed under Apache-2.0, and ranks #13,622 globally. It is actively maintained with the latest commit recorded on Nov 12, 2026.”
| Repository | openvax/pyensembl ↗ |
|---|---|
| Primary Category | developer tools |
| Language & Stack | Python |
| Software License | Apache-2.0 |
| Community Traction | ★ 411 stars · ⑂ 75 forks · #13,622 globally |
| Maintenance | ● Active (Last commit: Nov 12, 2026) · 19 open issues |
| Target Audience | Developers and engineering teams building with Python, seeking reliable, tested, and actively maintained tooling for production workloads. |
🛡️ Repository Maintenance & Health Audit (2026)
Health Score: 93/100 · Grade A+Yes, pyensembl is actively maintained. Continuous telemetry recorded the last code commit on Nov 12, 2026 (0 days ago). Supported by 411 stars and 75 community forks, this repository holds a calculated health index of 93/100, reflecting very active (commits within last 14 days) and healthy issue cadence.
Star History
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+10
STARS · LAST 30 DAYS
1
PER DAY
#1,834
MOST-STARRED Python
| Window | 7 days | 30 days | 90 days |
|---|---|---|---|
| Stars gained | +7 | +10 | +90 |
| Per day | 1 | 1 | 1 |
| Forks gained | +1 | +3 | +10 |
pyensembl gained 10 stars in the last 30 days, about 1 a day, and now has 411. It is about 13 years old and has averaged roughly 32 stars a year. It ranks #1,834 among Python repositories and #13,622 across all languages on GitHubRepo.
Trending Record
1
DAYS ON TRENDING
#16045
BEST RANK
Nov 12, 2026
FIRST APPEARANCE
Active
STATUS TODAY
pyensembl has maintained a continuous presence across global trending indexes, peaking at #16045. Below is the 30-day activity profile:
💡 Overview
pyensembl is an open-source project written in Python: Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl .
Engineered for speed, consistency, and developer ease, it solves common hurdles in Python. It provides clear interfaces, comprehensive configuration options, and seamless integration with existing tools across the modern development stack.
⚡ Key Features
Optimized execution pipeline written in Python for predictable speed.
Zero-friction configuration with comprehensive sensible defaults out of the box.
Cross-platform runtime support across Linux, macOS, and Windows environments.
Strong typing and modular architecture designed for easy extension and maintainability.
Standardized CLI and API interfaces for smooth integration into CI/CD workflows.
Active community maintenance with regular dependency updates and security patches.
📥 Installation
$ pip install pyensembl⚙ System Requirements
Platforms
- • macOS
- • Linux
- • Windows
Runtime & Dependencies
Python >= 3.9, pip, virtualenv
Architecture
x86_64, ARM64 (Apple Silicon & Graviton)
🧠 How It Works
pyensembl coordinates its core functionality through a modular Python pipeline. It parses configuration parameters, validates inputs, and resolves dependencies asynchronously. By minimizing runtime overhead and keeping allocations localized, it delivers predictable performance in both local development environments and automated production workloads.
🎯 Production Use Cases
Production System Integration
Embed pyensembl into Python backend services to handle core application logic.
CI/CD Automated Pipelines
Run automated validation, builds, and integration suites during deployments.
Developer Tooling & Workflows
Accelerate developer onboarding with pre-configured project utilities.
Open Source Extension
Fork and customize internal modules under the repository's open Apache-2.0 license.
🚀 Getting Started
Install pyensembl using your package manager: `pip install pyensembl`
Initialize your project workspace or configuration file for pyensembl.
Import pyensembl into your codebase or invoke it directly from your terminal.
Execute your test suite or run `pyensembl --help` to verify successful setup.
👍 Strengths
⚠️ Considerations
⇄ Alternatives & Direct Competitors
👥 Who Should Use This
Developers and engineering teams building with Python, seeking reliable, tested, and actively maintained tooling for production workloads.
🏆 Nearby in the Rankings
openvax/pyensembl is currently ranked #13,622 by stars across every repository tracked on GitHubRepo. These are adjacent projects:
| Rank | Repository | Language | Stars | Action |
|---|---|---|---|---|
| #13,614 | aalykiot/dune | Rust | ★ 412 | Compare ↗ |
| #13,614 | Corsinvest/cv4pve-admin | C# | ★ 412 | Compare ↗ |
| #13,614 | ohdearquant/lionagi | Python | ★ 412 | Compare ↗ |
| #13,614 | basecamp/hey-cli | Go | ★ 412 | Compare ↗ |
| #13,614 | scaleapi/agentenv-framework | Python | ★ 412 | Compare ↗ |
| #13,622 | openvax/pyensembl This Project | Python | ★ 411 | |
| #13,622 | bfirsh/django-shorturls | Python | ★ 411 | Compare ↗ |
| #13,622 | makerbot/ReplicatorG | Python | ★ 411 | Compare ↗ |
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Frequently Asked Questions
What does pyensembl do? +
Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl
Is pyensembl actively maintained in 2026? +
Yes, pyensembl is actively maintained. The latest code push was recorded on Nov 12, 2026 (0 days ago). It holds a calculated Maintenance Health Score of 93/100 (A+ rating) with 411 stars and 19 open issues.
What language is pyensembl written in? +
The primary language is Python. Topics include: software.
How many stars does pyensembl have? +
pyensembl has 411 stars and 75 forks on GitHub.
How does pyensembl rank among GitHub repositories? +
With 411 stars, openvax/pyensembl is ranked #13,622 globally across all repositories tracked on GitHubRepo and #1,834 among Python projects.
What license is pyensembl distributed under? +
The repository reports a Apache-2.0 license. Always verify the repository LICENSE file for legal terms.
