Top Python GitHub Repositories & Open Source Projects (2026)

A Home Assistant HACS integration that supports Kia Connect(Uvo) and Hyundai Bluelink. The integration supports the EU, Canada and the USA.

Enterprise-ready MCP Gateway & Registry that centralizes AI development tools with secure OAuth authentication, dynamic tool discovery, and unified access for both autonomous AI agents and AI coding assistants. Transform scattered MCP server chaos into governed, auditable tool access with Keycloak/Entra integration.

SCCMHunter is a post-ex tool built to streamline identifying, profiling, and attacking SCCM related assets in an Active Directory domain.

FlagGems is an operator library for large language models implemented in the Triton Language.

A simple Minecraft modpack focusing on performance and graphics enhancements.

Bayesian marketing toolbox in PyMC. Media Mix (MMM), customer lifetime value (CLV), buy-till-you-die (BTYD) models and more.

The backend agents build with - Multimodal database, orchestration, and serving in one file

Music player and music library manager for Linux, Windows, and macOS

Web vulnerability scanner written in Python3

Auto-configure and then control your Midea M-Smart devices (Air conditioner, Fan, Water heater, Washer, etc) via local area network.

Nix User Repository: User contributed nix packages [maintainer=@Pandapip1]

An implementation of chunked, compressed, N-dimensional arrays for Python.

A simple, performant, and scalable Jax LLM!

Interactive architecture diagrams for codebases

Wizarr is an advanced user invitation and management system for Jellyfin, Plex, Emby etc.

The official gpt4free repository | various collection of powerful language models | opus 4.6 gpt 5.3 kimi 2.5 deepseek v3.2 gemini 3

Open-source AI penetration testing tool to find and fix your app’s vulnerabilities.

Deep Learning for humans

Ultralytics YOLO27, YOLO26, YOLO11, YOLOv8 — object detection, instance segmentation, semantic segmentation, image classification, pose estimation, object tracking

PennyLane is an open-source quantum software platform for quantum computing, quantum machine learning, and quantum chemistry. Create meaningful quantum algorithms, from inspiration to implementation.