Top Python GitHub Repositories & Open Source Projects (2026)

Open source local-first PR scanner that finds dead code, security bugs, secrets, quality regressions, and AI-code mistakes before merge. For first timers refer to https://duriantaco.github.io/skylos/repo-map/

Free, open-source, 100% offline voice dictation for Linux. Speak and type anywhere via whisper.cpp, Whisper & VOSK engines, GPU-accelerated, works on X11 + Wayland!

A Home Assistant HACS integration that supports Kia Connect(Uvo) and Hyundai Bluelink. The integration supports the EU, Canada and the USA.

Enterprise-ready MCP Gateway & Registry that centralizes AI development tools with secure OAuth authentication, dynamic tool discovery, and unified access for both autonomous AI agents and AI coding assistants. Transform scattered MCP server chaos into governed, auditable tool access with Keycloak/Entra integration.

SCCMHunter is a post-ex tool built to streamline identifying, profiling, and attacking SCCM related assets in an Active Directory domain.

FlagGems is an operator library for large language models implemented in the Triton Language.

A simple Minecraft modpack focusing on performance and graphics enhancements.

Bayesian marketing toolbox in PyMC. Media Mix (MMM), customer lifetime value (CLV), buy-till-you-die (BTYD) models and more.

The backend agents build with - Multimodal database, orchestration, and serving in one file

Web vulnerability scanner written in Python3

Auto-configure and then control your Midea M-Smart devices (Air conditioner, Fan, Water heater, Washer, etc) via local area network.

Nix User Repository: User contributed nix packages [maintainer=@Pandapip1]

An implementation of chunked, compressed, N-dimensional arrays for Python.

A simple, performant, and scalable Jax LLM!

Interactive architecture diagrams for codebases

LinuxCNC controls CNC machines. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.

Wizarr is an advanced user invitation and management system for Jellyfin, Plex, Emby etc.

The official gpt4free repository | various collection of powerful language models | opus 4.6 gpt 5.3 kimi 2.5 deepseek v3.2 gemini 3

Open-source AI penetration testing tool to find and fix your app’s vulnerabilities.

Deep Learning for humans