EllisLab's Open Source PHP Framework
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Jo (0.5.0) is a thin (~16K) candy shell for making HTML5 apps. Jo works with: PhoneGap, Chrome, Safari, Opera, FireFox, iOS, Android, BlackBerry 10, Tizen, & Windows Phone 8+. Features include skinnable UI widgets, a clean event model and a light data layer.
cocos2d for iOS, Android, Win32 and OS X. Built using C++
The HTML5 Media Framework
A framework for developers who want to design, build and share cross device applications.