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Ohio State puts its 22-game winning streak on the line when it welcomes Indiana into Columbus this Saturday. The Buckeyes are 35-point favorites, according to Vegas Insider's consensus, so it's safe to say that the Buckeyes will almost certainly push their winning streak to 23 games. However, it's often been the more average teams that have given OSU the most problems in recent years. Just this season, the Buckeyes were in a dogfight with Iowa. While Ohio State prevailed, it had to give fans enough of a scare.