Python Koans - Learn Python through TDD
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aka "Bayesian Methods for Hackers": An introduction to Bayesian methods + probabilistic programming with a computation/understanding-first, mathematics-second point of view. All in pure Python ;)
The official online compendium for Mining the Social Web (O'Reilly, 2011)
Flexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, statistical functions, and much more
Scrapy, a fast high-level screen scraping and web crawling framework for Python.