Top Python GitHub Repositories & Open Source Projects (2026)

Agent Skills for NVIDIA products — install into Claude Code, Codex, and other coding agents to run Physical AI, robotics, simulation, CUDA, and RAG workflows end to end.

Python script to update metadata information for items in plex as well as automatically build collections and playlists. The Wiki Documentation is linked below.

Amazon Bedrock Agentcore accelerates AI agents into production with the scale, reliability, and security, critical to real-world deployment.

Connect any AI copilot or autonomous agent to your enterprise tools — through a single, secure MCP/Agent gateway with built-in identity, access control, and full observability.

Free vless-vmess-shadowsocks-trojan-xray-V2ray Configs Updating Every 5 minutes

A python CAD programming library

Kubernetes operator for managing the lifecycle of Apache Spark applications on Kubernetes.

Source code for Gramps Genealogical program

Your Bambu Lab. No Cloud. Your Rules. Self-hosted command center for Bambu Lab — from one A1 to an entire print farm.

A fully tested, abstract interface to creating OAuth clients and servers.

Modding platform for GI, HSR, WW and ZZZ

Persistent remote applications for X11; screen sharing for X11, MacOS and MSWindows.

Data manipulation and transformation for audio signal processing, powered by PyTorch

A :baby: buddy to help caregivers track sleep, feedings, diaper changes, tummy time and more to learn about and predict baby's needs without (as much) guess work.

Open-source, self-hosted AI penetration testing framework: maps your attack surface into a graph, autonomously exploits it from a Kali sandbox with human approval gates, and opens PRs that fix what it finds. MCP both ways: plug in any MCP server as a tool, or drive RedAmon from Claude Code or your own agent.

Inspect: A framework for large language model evaluations

A Python port of Pi’s minimalist coding agent.

A Python library for reading and writing PDF, powered by QPDF

A static website and blog generator

MCP server that lets Claude Code and other AI agents read and search large PDFs, one file or a whole folder: agentic RAG with hybrid semantic + keyword search, selective page reads, tables, images, OCR, chart data, and multi-column/CJK layouts.