Top Python GitHub Repositories & Open Source Projects (2026)

Astra plans and reviews; DeepSeek Flash builds. A native Codex workflow with phased tasks, verification, safe installation and reversible setup.

pyHanko: sign and stamp PDF files

A mascot that watches the cursor and blinks when you poke it

Open source local-first PR scanner that finds dead code, security bugs, secrets, quality regressions, and AI-code mistakes before merge. For first timers refer to https://duriantaco.github.io/skylos/repo-map/

Free, open-source, 100% offline voice dictation for Linux. Speak and type anywhere via whisper.cpp, Whisper & VOSK engines, GPU-accelerated, works on X11 + Wayland!

A Home Assistant HACS integration that supports Kia Connect(Uvo) and Hyundai Bluelink. The integration supports the EU, Canada and the USA.

Enterprise-ready MCP Gateway & Registry that centralizes AI development tools with secure OAuth authentication, dynamic tool discovery, and unified access for both autonomous AI agents and AI coding assistants. Transform scattered MCP server chaos into governed, auditable tool access with Keycloak/Entra integration.

SCCMHunter is a post-ex tool built to streamline identifying, profiling, and attacking SCCM related assets in an Active Directory domain.

Stop your AI from making things up — it proposes, deterministic tools decide, every claim checked against ground truth with evidence. Grounded facts and context survive resets. Reverse engineering is the proving ground. MCP server + CLI.

Bayesian marketing toolbox in PyMC. Media Mix (MMM), customer lifetime value (CLV), buy-till-you-die (BTYD) models and more.

The backend agents build with - Multimodal database, orchestration, and serving in one file

Web vulnerability scanner written in Python3

Nix User Repository: User contributed nix packages [maintainer=@Pandapip1]

A simple, performant, and scalable Jax LLM!

Interactive architecture diagrams for codebases

LinuxCNC controls CNC machines. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.

Wizarr is an advanced user invitation and management system for Jellyfin, Plex, Emby etc.

Open-source AI penetration testing tool to find and fix your app’s vulnerabilities.

Deep Learning for humans

Ultralytics YOLO27, YOLO26, YOLO11, YOLOv8 — object detection, instance segmentation, semantic segmentation, image classification, pose estimation, object tracking